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Statistical Design and Evaluation of Biomarker Studies
We review biostatistical aspects of biomarker studies, including design and anal
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PKR in Innate Immunity, Cancer, and Viral Oncolysis
The mammalian innate immune system provides a first line of defense against micr
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Magnetic Resonance Imaging of Tumor Response to Chemotherapy
The breadth and substance of anatomic (structural) and novel physiological (func
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TNF Signaling: Key Protocols
Tumor necrosis factor (TNF) is a pleiotropic cytokine that signals inflammation
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In Vitro Testing of Chemosensitivity in Physiological Hypoxia
Highly aggressive, rapidly growing tumors are often hypoxic, owing to an inadequ
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Role of Tumor Suppressors in DNA Damage Response
Studies of human cancer predisposition syndromes and mouse knockout models have
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Expression Profiling of Lung Cancer Based on Suppression Subtraction Hybridization (SSH)
Gene amplifications and deletions frequently contribute to tumorigenesis. The ch
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Synthesis, Characterization, and Functionalization of Gold Nanoparticles for Cancer Imaging
This chapter describes the methodology by which mAb-F19-conjugated gold nanopart
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Mutational Analysis of the Androgen Receptor Using Laser Capture Microdissection and Direct Sequenci
Molecular analysis of prostate cancer specimens is complicated by tumor heteroge
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Assessment of Resistance to Anoikis in Ovarian Cancer
Anoikis, a form of programmed cell death that occurs due to cell detachment from
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Detection of BCR-ABL in Hematological Malignancies by RT-PCR
The presence of a novel, minute chromosome m the cells of patients with chrome m
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T-Cell Receptor Molecular Diagnosis of T-Cell Lymphoma
Malignant and reactive lymphoproliferations in most cases can be distinguished b
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Assembling a Tumor Progression Model
Tumor progression can very broadly be def ined as the progression from a less ad
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Chemosensitivity Testing Using Microplate Adenosine Triphosphate-Based Luminescence Measurements
During the last two decades, novel nonclonogenic methods for pretherapeutic chem
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Targeted Delivery of Expression Plasmids to the Lung via Macroaggregated Polyethylenimine-Albumin Co
Gene therapy for lung cancer has great potential to treat and possibly cure one
