In Vivo Microbial Antigen Discovery (InMAD) to Identify Diagnostic Proteins and Polysaccharides That
Immunoassays employed at the point-of-care (POC) are often useful for diagnosing
Immunoassays employed at the point-of-care (POC) are often useful for diagnosing acute infections. Many of these assays rely on identification of microbial antigens that are secreted or shed during infection. However, determining which microbial antigens are best to target by immunoassay can be the most difficult aspect of developing a new diagnostic product. Here we describe a novel technique termed “In vivo Microbial Antigen Discovery” or “InMAD” for identification of microbial antigens that may be targeted for the diagnosis of infectious diseases.
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In Vivo Models for Studying Mast Cell-Dependent Responses to Bacterial Infection
Mast cells are a critical component of host defense against ...
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In Vivo Method for Establishing Synergy Between Antibodies to Epidermal Growth Factor Receptor and V
Targeted therapy for cancer is shifting towards an approach ...