CD47/CD47R分子

CD47/CD47R 分子

CD47

常用单克隆抗体或代号： BRIC126,CIKM1

主要表达细胞： 广泛 [AS]

分子质量(kDa)和结构： gp47,N连接葡萄糖

功 能： 粘附分子相关信号分子

CD47R

常用单克隆抗体或代号：(为原CDw149)MEM―33

主要表达细胞：广泛[NL]

CD47 Aka integrin associated protein (IAP); one of many thrombospondin receptors Similar to Rh-antigen May interact with integrins and mediate intracellular calcium increase during cell adhesion May help macrophages distinguish self from foreign substances May have role in giant cell creation from macrophage fusion Positive staining (normal): hemaoietic cells, epithelial cells, endothelial cells, fibroblasts, mesenchymal cells Positive staining (disease): tumor cell lines CD47R Aka Rh related antigen Similar to Rh-antigen; may interact with integrins Previously CDw149