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  • DNA Sequencing of Cancer-Related Genes for Biomarker Discovery

    DNA Sequencing of Cancer-Related Genes for Biomarker Discovery

    Dideoxy DNA sequencing is routinely used in research and, increasingly, in clini

    2025-03-17 44
  • Biochemical Analysis of the Cell Cycle and Cell Cycle Checkpoints in Transiently Transfected Cells A

    Biochemical Analysis of the Cell Cycle and Cell Cycle Checkpoints in Transiently Transfected Cells A

    It is frequently necessary to examine the biochemical effects of ectopically exp

    2025-03-17 48
  • The MTT Assay to Evaluate Chemosensitivity

    The MTT Assay to Evaluate Chemosensitivity

    The assessment of the degree or rate of cellular proliferation and cell viabilit

    2025-03-17 49
  • Polymorphisms of DNA Repair Genes: ADPRT, XRCC1, and XPD and Cancer Risk in Genetic Epidemiology

    Polymorphisms of DNA Repair Genes: ADPRT, XRCC1, and XPD and Cancer Risk in Genetic Epidemiology

    Many studies have suggested that adenosine diphosphate ribosyl transferase (ADPR

    2025-03-17 37
  • Immunohistochemical Analysis for hMLH1 and hMSH2 Expression in Colorectal Cancer

    Immunohistochemical Analysis for hMLH1 and hMSH2 Expression in Colorectal Cancer

    Defective DNA mismatch repair (MMR) occurs in the majority of tumors from patien

    2025-03-17 37
  • Differential Expression of Apoptosis-Associated Genes bax and bcl-2 in Ovarian Cancer

    Differential Expression of Apoptosis-Associated Genes bax and bcl-2 in Ovarian Cancer

    The deregulation of the balance between proliferation and programmed cell death

    2025-03-17 34
  • Gene Therapy in Melanoma

    Gene Therapy in Melanoma

    The identification of genes involved in different biologic functions and in the

    2025-03-17 38
  • Chemopreventive Therapeutics: Inhalation Therapies for Lung Cancer and Bronchial Premalignancy

    Chemopreventive Therapeutics: Inhalation Therapies for Lung Cancer and Bronchial Premalignancy

    Lung cancer is the number one cause of cancer-related death in the US. In 2001,

    2025-03-17 36
  • Detecting and Modulating the NF-kB Activity in Human Immune Cells: Generation of Human Cell Lines wi

    Detecting and Modulating the NF-kB Activity in Human Immune Cells: Generation of Human Cell Lines wi

    NF-κB plays a pivotal role in immunity and inflammation and is considered to be

    2025-03-17 33
  • Molecular Genetic Analysis of Flow-Sorted and Microdissected Ovarian Tumor Cells Improved Detection

    Molecular Genetic Analysis of Flow-Sorted and Microdissected Ovarian Tumor Cells Improved Detection

    Study of loss of heterozygosity (LOH) is widely used to identify chromosomal loc

    2025-03-17 41
  • Different Study Designs in the Epidemiology of Cancer: Case-Control vs. Cohort Studies

    Different Study Designs in the Epidemiology of Cancer: Case-Control vs. Cohort Studies

    It is only since the 1950s that most of the epidemiology studies on cancer have

    2025-03-17 38
  • Identification of Mutations in the Retinoblastoma Gene

    Identification of Mutations in the Retinoblastoma Gene

    Mutations in the retinoblastoma gene (RBl) predispose to the formation of ocular

    2025-03-17 36
  • Isolation of Melanoma Cell Subpopulations Using Negative Selection

    Isolation of Melanoma Cell Subpopulations Using Negative Selection

    Melanomas are phenotypically and functionally heterogeneous tumors comprising of

    2025-03-17 28
  • WT-1 Overexpression in Acute Myeloid Leukemia and Myelodysplastic Syndromes

    WT-1 Overexpression in Acute Myeloid Leukemia and Myelodysplastic Syndromes

    The Wilms tumor gene was identified as a tumor suppressor gene responsible for a

    2025-03-17 34
  • Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy

    Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy

    Members of the tumor necrosis factor (TNF) superfamily influence a variety of im

    2025-03-17 34