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DNA Sequencing of Cancer-Related Genes for Biomarker Discovery
Dideoxy DNA sequencing is routinely used in research and, increasingly, in clini
2025-03-17 44 -
Biochemical Analysis of the Cell Cycle and Cell Cycle Checkpoints in Transiently Transfected Cells A
It is frequently necessary to examine the biochemical effects of ectopically exp
2025-03-17 48 -
The MTT Assay to Evaluate Chemosensitivity
The assessment of the degree or rate of cellular proliferation and cell viabilit
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Polymorphisms of DNA Repair Genes: ADPRT, XRCC1, and XPD and Cancer Risk in Genetic Epidemiology
Many studies have suggested that adenosine diphosphate ribosyl transferase (ADPR
2025-03-17 37 -
Immunohistochemical Analysis for hMLH1 and hMSH2 Expression in Colorectal Cancer
Defective DNA mismatch repair (MMR) occurs in the majority of tumors from patien
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Differential Expression of Apoptosis-Associated Genes bax and bcl-2 in Ovarian Cancer
The deregulation of the balance between proliferation and programmed cell death
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Gene Therapy in Melanoma
The identification of genes involved in different biologic functions and in the
2025-03-17 38 -
Chemopreventive Therapeutics: Inhalation Therapies for Lung Cancer and Bronchial Premalignancy
Lung cancer is the number one cause of cancer-related death in the US. In 2001,
2025-03-17 36 -
Detecting and Modulating the NF-kB Activity in Human Immune Cells: Generation of Human Cell Lines wi
NF-κB plays a pivotal role in immunity and inflammation and is considered to be
2025-03-17 33 -
Molecular Genetic Analysis of Flow-Sorted and Microdissected Ovarian Tumor Cells Improved Detection
Study of loss of heterozygosity (LOH) is widely used to identify chromosomal loc
2025-03-17 41 -
Different Study Designs in the Epidemiology of Cancer: Case-Control vs. Cohort Studies
It is only since the 1950s that most of the epidemiology studies on cancer have
2025-03-17 38 -
Identification of Mutations in the Retinoblastoma Gene
Mutations in the retinoblastoma gene (RBl) predispose to the formation of ocular
2025-03-17 36 -
Isolation of Melanoma Cell Subpopulations Using Negative Selection
Melanomas are phenotypically and functionally heterogeneous tumors comprising of
2025-03-17 28 -
WT-1 Overexpression in Acute Myeloid Leukemia and Myelodysplastic Syndromes
The Wilms tumor gene was identified as a tumor suppressor gene responsible for a
2025-03-17 34 -
Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
Members of the tumor necrosis factor (TNF) superfamily influence a variety of im
2025-03-17 34