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  • Gene Therapy Vectors Harboring AFP Regulatory Sequences: Preparation of an Adenoviral Vector

    Gene Therapy Vectors Harboring AFP Regulatory Sequences: Preparation of an Adenoviral Vector

    A goal of cancer research is to develop therapies that can selectively kill tumo

    2025-03-17 38
  • Bcl-2 Family Immunohistochemistry

    Bcl-2 Family Immunohistochemistry

    In recent years, immunohistochemistry as applied to the Bcl-2 family of proteins

    2025-03-17 41
  • Comparative Genomic Hybridization Technique

    Comparative Genomic Hybridization Technique

    Screening for chromosomal changes in solid tumors was long hindered by methodolo

    2025-03-17 35
  • Novel Effective Tumor Vaccines for Hepatocellular Carcinoma

    Novel Effective Tumor Vaccines for Hepatocellular Carcinoma

    Hepatocellular carcinoma (HCC) is one of the most frequent malignancies in numer

    2025-03-17 38
  • Genome-Wide DNA Methylation Profiling: The mDIP-Chip Technology

    Genome-Wide DNA Methylation Profiling: The mDIP-Chip Technology

    Aberrant DNA methylation is one of the major characteristics of tumor cells in a

    2025-03-17 36
  • Hybrid Capture of Putative Tumor Suppressor Genes

    Hybrid Capture of Putative Tumor Suppressor Genes

    During the last part of the twentieth century, research on human cancer increasi

    2025-03-17 38
  • Zoom-In Array Comparative Genomic Hybridization (aCGH) to Detect Germline Rearrangements in Cancer S

    Zoom-In Array Comparative Genomic Hybridization (aCGH) to Detect Germline Rearrangements in Cancer S

    Disease predisposing germline mutations in cancer susceptibility genes may consi

    2025-03-17 45
  • Analysis of the Spindle-Assembly Checkpoint in HeLa Cells

    Analysis of the Spindle-Assembly Checkpoint in HeLa Cells

    The spindle-assembly checkpoint involves signaling at kinetochores, which leads

    2025-03-17 36
  • Assessing Matrix Metalloproteinase Expression and Activity in Hepatocellular Carcinomas

    Assessing Matrix Metalloproteinase Expression and Activity in Hepatocellular Carcinomas

    The matrix metalloproteinases (MMPs) constitute a large family of zincand calciu

    2025-03-17 43
  • Glycoproteomic Analysis by Two-Dimensional Electrophoresis

    Glycoproteomic Analysis by Two-Dimensional Electrophoresis

    Changes in N-linked glycosylation are known to occur during the development of c

    2025-03-17 31
  • Application of Recombinant Antibodies in Cancer Patients

    Application of Recombinant Antibodies in Cancer Patients

    As a consequence of the invention of the hybridoma technology by K�hler and Mils

    2025-03-17 31
  • Fluorescence In Situ Hybridization for Cancer-Related Studies

    Fluorescence In Situ Hybridization for Cancer-Related Studies

    Cytogenetic analysis of tumour material has been greatly enhanced over the past

    2025-03-17 30
  • Immunocytochemical Detection and Characterisation of Individual Micrometastatic Tumour Cells

    Immunocytochemical Detection and Characterisation of Individual Micrometastatic Tumour Cells

    Detection of micrometastases in the bone marrow (BM) of cancer patients may be a

    2025-03-17 33
  • Somatic Cell Knockouts of Tumor Suppressor Genes

    Somatic Cell Knockouts of Tumor Suppressor Genes

    Gene targeting is the modification of specific DNA sequences in a living organis

    2025-03-17 42
  • Clonality Analysis by T-Cell Receptor PCR and High-Resolution Electrophoresis in the Diagnosis of Cu

    Clonality Analysis by T-Cell Receptor PCR and High-Resolution Electrophoresis in the Diagnosis of Cu

    During T-cell maturation, T-cell receptor (TCR) gene segments rearrange, resulti

    2025-03-17 55