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Tissue Culture Correlational Study of Genetic Cholangiopathy of Autosomal Recessive Polycystic Kidne
Cholangiocytes are epithelial cells that line the biliary tract and are also kno
2025-02-11 5 -
From Gene-Scale to Genome-Scale Phylogenetics: the Data Flood In, but the Challenges Remain
An important goal of phylogenetics is to be able to consistently and accurately
2025-02-11 5 -
Study Design: The Basics
In biomedical research, meaningful conclusions can only be drawn based on data c
2025-02-11 5 -
Mouse Models of Triplet Repeat Diseases
Since their discovery in 1991, triplet repeat mutations have been found to be th
2025-02-11 7 -
Detection of Cytoplasmic and Nuclear Functions of mTOR by Fractionation
Subcellular localization constitutes the environment in which proteins act. It t
2025-02-11 5 -
Isolation of Focal Adhesion Proteins for Biochemical and Proteomic Analysis
Focal adhesions (FAs) are discrete plasma membrane-associated adhesive organelle
2025-02-11 8 -
Live Imaging for Studying Asymmetric Cell Division in the C. elegans Embryo
Asymmetric cell division is essential during development to generate cell divers
2025-02-11 8 -
Organotypic raft culture of primary human keratinocytes (PHKs)
Organotypic raft culture of primary human keratinocytes (PHKs)NotesUse 106 kerat
2025-02-11 5 -
Application of Plastic Embedding for Sectioning Whole-Mount Immunostained Early Vertebrate Embryos
Development of tissues and organs relies on the constant interplay of intracellu
2025-02-11 6 -
Purification and Characterization of Viral dsRNA Genome Profiles by Crosshybridization
Double-stranded (ds) RNA present as genetic elements are widely distributed in n
2025-02-11 6 -
Analysis of Cell Death by Electron Microscopy
Cell death is said to occur mostly by two alternative, opposite modes: apoptosis
2025-02-11 4 -
Imaging of Embryonic Stem Cell Migration In Vivo
Conventional reporter gene technology and histological methods cannot routinely
2025-02-11 6 -
非内共生学说
又称细胞内分化学说。认为线粒体的发生是质膜内陷的结果。有几种模型,其中Uzzell的模型认为:在进化的最初阶段,原核细胞基因组进行复制,并不伴有细胞分裂,而是在
2025-02-11 7 -
流式细胞术:标本处理
一、 流式 细胞术常规检测时的样品制备(一)直接免疫荧光标记法取一定量细胞(约1X106 细胞/ml),在每一管中分别加入50μl的HAB,并充分混匀,于室温中
2025-02-11 9 -
PI3K-Akt信号通路的抑制位点
相关专题 PI3K和其下游分子 所转导的抗凋亡信号已经成为药物研究领域的焦点, 目前用于抑制该信号通路的策略主要有以下几个方面:1.发展和应用小分子 抑制剂目
2025-02-11 19