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  • Caspase Activity Assays

    Caspase Activity Assays

    Caspase activity assays in multi-well plate formats represent powerful tools for

    2025-03-15 52
  • Selection of Cytochrome P450 Genes for Use in Prodrug Activation-Based Cancer Gene Therapy

    Selection of Cytochrome P450 Genes for Use in Prodrug Activation-Based Cancer Gene Therapy

    Prodrug activation-based cancer gene therapy is a molecular strategy to improve

    2025-03-15 56
  • Electrophoretic Mobility Shift Analysis of the DNA Binding of Tumor Suppressor Gene Products

    Electrophoretic Mobility Shift Analysis of the DNA Binding of Tumor Suppressor Gene Products

    Central to the tumor suppressor activity of certain proteins is the ability to i

    2025-03-15 64
  • Application of SNP Genotype Arrays to Determine Somatic Changes in Cancer

    Application of SNP Genotype Arrays to Determine Somatic Changes in Cancer

    Genetic abnormalities in leukaemia range from single gene defects to chromosomal

    2025-03-15 50
  • Detection of K-ras Mutations by a Microelectronic DNA Chip

    Detection of K-ras Mutations by a Microelectronic DNA Chip

    The increased knowledge of the human genome, thanks to its sequencing and to the

    2025-03-15 64
  • Integrating Multiple Clinical Tests to Increase Predictive Power

    Integrating Multiple Clinical Tests to Increase Predictive Power

    Clinical tests provide information that can be used by statistical methods to ma

    2025-03-15 48
  • Generation and Application of Phospho-specific Antibodies for p53 and pRB

    Generation and Application of Phospho-specific Antibodies for p53 and pRB

    The functions of many proteins are likely to be regulated by phosphorylation. Th

    2025-03-15 38
  • Tumor Vascular Therapy With TNF: Critical Review on Animal Models

    Tumor Vascular Therapy With TNF: Critical Review on Animal Models

    To study tumor therapeutic treatment modalities, whether from a clinical, precli

    2025-03-15 53
  • Quantitation of CD39 Gene Expression in Pancreatic Tissue by Real-Time Polymerase Chain Reaction

    Quantitation of CD39 Gene Expression in Pancreatic Tissue by Real-Time Polymerase Chain Reaction

    Within the past decade, the field of gene expression analysis has constantly evo

    2025-03-15 42
  • Authentication of Cancer Cell Lines by DNA Fingerprinting

    Authentication of Cancer Cell Lines by DNA Fingerprinting

    The requirement for authentication of cell lines has a history almost as long as

    2025-03-15 40
  • Tumor-Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis

    Tumor-Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis

    The role of the tumor-infiltrating lymphocyte (TIL) and its relationship to prog

    2025-03-15 43
  • Aerosol Gene Therapy for Metastatic Lung Cancer Using PEI-p53 Complexes

    Aerosol Gene Therapy for Metastatic Lung Cancer Using PEI-p53 Complexes

    Inactivation of p53wt, a tumor-suppressor gene, has been observed in a majority

    2025-03-15 47
  • Molecular Analysis of the von Hippel-Lindau Disease Gene

    Molecular Analysis of the von Hippel-Lindau Disease Gene

    Von Hippel-Lindau (VHL) disease is an autosomal dominant disorder that predispos

    2025-03-15 47
  • Recent Advances and Dilemmas in the Radiotherapeutic Management of Locally Advanced Non-Small Cell L

    Recent Advances and Dilemmas in the Radiotherapeutic Management of Locally Advanced Non-Small Cell L

    During the 1990s, thoracic radiotherapy (RT) combined with chemotherapy was acce

    2025-03-15 32
  • Generation of Recombinant Multimeric Antibody Fragments for Tumor Diagnosis and Therapy

    Generation of Recombinant Multimeric Antibody Fragments for Tumor Diagnosis and Therapy

    Single chain recombinant antibody fragments can multimerise to provide high bind

    2025-03-15 45