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RT-PCR Analysis of Breakpoints Involving the MLL Gene Located at 11q23 in Acute Leukemia
Chromosome rearrangements of chromosome 11 at band 1 1q23 are detected in a high
2025-03-15 51 -
Factors Affecting Immunohistochemical Evaluation of Biomarker Expression in Neoplasia
Archival paraffin blocks frequently are studied to evaluate the expression of bi
2025-03-15 62 -
Storage of Cell Lines
The successful storage of cell lines depends upon many factors, including the co
2025-03-15 41 -
Assessment of Local Proteolytic Milieu as a Factor in Tumor Invasiveness and Metastasis Formation: I
Matrix invasion by a tumor cell requires the degradation of components in the ex
2025-03-15 49 -
Bisulfite Methylation Analysis of Tumor Suppressor Genes in Prostate Cancer from Fresh and Archival
It is now well established that, in addition to genetic changes that may include
2025-03-15 41 -
Developing Classifiers for the Detection of Cancer Using Multi-Analytes
The development of a successful classifier from multiple predictors (analytes) i
2025-03-15 36 -
Assaying the Spindle Checkpoint in the Budding Yeast Saccharomyces cerevisiae
The spindle checkpoint is assayed in Saccharomyces cerevisiae using several crit
2025-03-15 32 -
Detection of Rearrangements in the bcl-2 Gene Using the Polymerase Chain Reaction
Described here is a simple polymerase chain reaction (PCR) method for detecting
2025-03-15 31 -
Meta-analysis of Cancer Gene-Profiling Data
DNA microarray profiles are plagued by the issue of large number of variables bu
2025-03-15 31 -
Demonstration of a Germinal Center Immunophenotype in Lymphomas by Immunocytochemistry and Flow Cyto
The germinal center plays an important role in the pathogenesis of B-cell lympho
2025-03-15 31 -
Humanization of Monoclonal Antibodies by CDR Grafting
The discovery of the process for making rodent monoclonal antibodies (MAbs) 26 y
2025-03-15 32 -
Detection of Aberrant Glycosylation in Breast Cancer Using Lectin Histochemistry
Lectins are naturally occurring, carbohydrate-binding molecules that can be isol
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Detection of Telomerase Activity by PCR-Based Assay
Telomeres are distal ends of human chromosomes composed of tandem repeats of the
2025-03-15 34 -
Epigenetics in Ovarian Cancer
Ovarian cancer is the most lethal gynecological cancer. Due to few early symptom
2025-03-15 40 -
Use of DNA Fingerprinting to Detect Genetic Rearrangements in Human Cancer
The polymerase chain reaction (PCR) has revolutionized the isolation and analysi
2025-03-15 34