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  • RT-PCR Analysis of Breakpoints Involving the MLL Gene Located at 11q23 in Acute Leukemia

    RT-PCR Analysis of Breakpoints Involving the MLL Gene Located at 11q23 in Acute Leukemia

    Chromosome rearrangements of chromosome 11 at band 1 1q23 are detected in a high

    2025-03-15 51
  • Factors Affecting Immunohistochemical Evaluation of Biomarker Expression in Neoplasia

    Factors Affecting Immunohistochemical Evaluation of Biomarker Expression in Neoplasia

    Archival paraffin blocks frequently are studied to evaluate the expression of bi

    2025-03-15 62
  • Storage of Cell Lines

    Storage of Cell Lines

    The successful storage of cell lines depends upon many factors, including the co

    2025-03-15 41
  • Assessment of Local Proteolytic Milieu as a Factor in Tumor Invasiveness and Metastasis Formation: I

    Assessment of Local Proteolytic Milieu as a Factor in Tumor Invasiveness and Metastasis Formation: I

    Matrix invasion by a tumor cell requires the degradation of components in the ex

    2025-03-15 49
  • Bisulfite Methylation Analysis of Tumor Suppressor Genes in Prostate Cancer from Fresh and Archival

    Bisulfite Methylation Analysis of Tumor Suppressor Genes in Prostate Cancer from Fresh and Archival

    It is now well established that, in addition to genetic changes that may include

    2025-03-15 41
  • Developing Classifiers for the Detection of Cancer Using Multi-Analytes

    Developing Classifiers for the Detection of Cancer Using Multi-Analytes

    The development of a successful classifier from multiple predictors (analytes) i

    2025-03-15 36
  • Assaying the Spindle Checkpoint in the Budding Yeast Saccharomyces cerevisiae

    Assaying the Spindle Checkpoint in the Budding Yeast Saccharomyces cerevisiae

    The spindle checkpoint is assayed in Saccharomyces cerevisiae using several crit

    2025-03-15 32
  • Detection of Rearrangements in the bcl-2 Gene Using the Polymerase Chain Reaction

    Detection of Rearrangements in the bcl-2 Gene Using the Polymerase Chain Reaction

    Described here is a simple polymerase chain reaction (PCR) method for detecting

    2025-03-15 31
  • Meta-analysis of Cancer Gene-Profiling Data

    Meta-analysis of Cancer Gene-Profiling Data

    DNA microarray profiles are plagued by the issue of large number of variables bu

    2025-03-15 31
  • Demonstration of a Germinal Center Immunophenotype in Lymphomas by Immunocytochemistry and Flow Cyto

    Demonstration of a Germinal Center Immunophenotype in Lymphomas by Immunocytochemistry and Flow Cyto

    The germinal center plays an important role in the pathogenesis of B-cell lympho

    2025-03-15 31
  • Humanization of Monoclonal Antibodies by CDR Grafting

    Humanization of Monoclonal Antibodies by CDR Grafting

    The discovery of the process for making rodent monoclonal antibodies (MAbs) 26 y

    2025-03-15 32
  • Detection of Aberrant Glycosylation in Breast Cancer Using Lectin Histochemistry

    Detection of Aberrant Glycosylation in Breast Cancer Using Lectin Histochemistry

    Lectins are naturally occurring, carbohydrate-binding molecules that can be isol

    2025-03-15 35
  • Detection of Telomerase Activity by PCR-Based Assay

    Detection of Telomerase Activity by PCR-Based Assay

    Telomeres are distal ends of human chromosomes composed of tandem repeats of the

    2025-03-15 34
  • Epigenetics in Ovarian Cancer

    Epigenetics in Ovarian Cancer

    Ovarian cancer is the most lethal gynecological cancer. Due to few early symptom

    2025-03-15 40
  • Use of DNA Fingerprinting to Detect Genetic Rearrangements in Human Cancer

    Use of DNA Fingerprinting to Detect Genetic Rearrangements in Human Cancer

    The polymerase chain reaction (PCR) has revolutionized the isolation and analysi

    2025-03-15 34