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Helicobacter -Based Mouse Models of Digestive System Carcinogenesis
Animal models are necessary to reproduce the complex host, microbial and environ
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Mutational Screening of hMLH1 and hMSH2 that Confer Inherited Colorectal Cancer Susceptibility Using
Hereditary nonpolyposis colorectal cancer syndrome (HNPCC) is primarily due to h
2025-03-13 43 -
Mammographic Density: A Heritable Risk Factor for Breast Cancer
The appearance of the breast on mammography varies among women, reflecting varia
2025-03-13 39 -
Xenograft Models in Immunodeficient Animals: II. The Use of SCID Mice in Metastasis Research: Breast
Metastasis is a multistep phenomenon, and all steps have to be successfully and
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Hereditary Breast and Ovarian Cancer Genes
Breast cancer affects one out of every 10 women in industrialized countries, and
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Generation and Analysis of Brca1 Conditional Knockout Mice
Germline mutations of the breast tumor suppressor gene BRCA1 predispose women to
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Autoantibodies Against Cancer Antigens
With the identification of tumor antigens, the host immune response to various t
2025-03-13 40 -
Proteomics in the Analysis of Prostate Cancer
High-throughput DNA analysis has generated a wealth of information on predicted
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Gene Amplification of c-erbB-2 Detected by FISH
In 1981, a novel transforming gene called neu, related to, but distinct from, th
2025-03-13 45 -
Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era
The standard of care of patients with malignant melanoma is dramatically changin
2025-03-13 37 -
Primary Explant Cultures of Adult and Embryonic Pancreas
The developmental plasticity of adult pancreas is evidenced by the ability to un
2025-03-13 46 -
Regulation of NF-B by Oncoproteins and Tumor Suppressor Proteins
The transcription factor nuclear factor-κB (NF-κB) has been demonstrated to cont
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Localization of Cyclooxygenase-2 Protein Expression in Lung Cancer Specimens by Immunohistochemical
Cyclooxygenase-2 (COX-2) inhibitors comprise a group of compounds that show prom
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MTT Growth Assays in Ovarian Cancer
The MTT (3-[4,5-dimethylthiazol-2yl]-2,5-diphenyl tetrazolium bromide) growth as
2025-03-13 44 -
Apoptosis Detection by DNA Analysis
Apoptosis is a series of controlled sequential events resulting in cell death. T
2025-03-13 49
