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Laser-Assisted Microdissection and Isolation of DNA and RNA
One of the major challenges in molecular analysis of breast cancer specimens is
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Induced Nitric Oxide Synthase as a Major Player in the Oncogenic Transformation of Inflamed Tissue
Nitric oxide (NO) is a free radical that is involved in the inflammatory process
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Caspase-3 Activation is a Critical Determinant of Genotoxic Stress-Induced Apoptosis
A number of methods have been developed to identify the cells that undergo apopt
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Flow Cytometric MRD Detection in Selected Mature B-Cell Malignancies
The quantification of submicroscopic minimal residual disease (MRD) after therap
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Immunomagnetic Cell Separation
In metastasis research, it may sometimes be necessary to separate populations of
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Molecular Analysis of Cancer: An Overview
Cancer is a complex disease occurring as a result of a progressive accumulation
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Detecting Mismatch Repair Defects in Myeloma
Defects in the mismatch repair system are associated with a microsatellite unsta
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Gene Expression Profiling to Characterize Anticancer Drug Sensitivity
This chapter presents a protocol for using cDNA microarrays to acquire gene expr
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Immunohistochemistry of p53, Bcl-2, and Ki-67 as Predictors of Chemosensitivity
Chemosensitivity is affected by molecular biological factors, including factors
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DNA-Dependent Protein Kinase in Apoptosis
Programmed cell death or apoptosis can be induced by a variety of mechanisms inc
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PARP Cleavage as a Means of Assessing Apoptosis
Although cell death is often seen as a pathological process, there are classical
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Dietary and Lifestyle Factors of DNA Methylation
Lifestyle factors, such as diet, smoking, physical activity, and body weight man
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Biomarkers of Cell Proliferation in Carcinomas: Detection of Angiogenesis and Infiltrated Leukocytes
Angiogenesis is an important marker for tumor growth, development, and metastasi
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Traditional and Established Indicators of Prognosis and Treatment Success
The outcome of breast cancer in an individual patient can be predicted by assess
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Calibration of Microarray Gene-Expression Data
Calibration of microarray measurements aims at removing systematic biases from t
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