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Enzyme Analysis: Cathepsin D as an Example
In enzyme analysis, capillary electrophoresis (CE) offers the ease of product se
2025-01-21 11 -
Membrane Partitioning and Translocation Studied by Isothermal Titration Calorimetry
The ability to bind to and translocate across lipid bilayers is of paramount imp
2025-01-21 7 -
Regulation of Apoptosis by the Unfolded Protein Response
In eukaryotic cells, the endoplasmic reticulum (ER) serves many specialized func
2025-01-21 8 -
Utility of Antioncogene Ribozymes and Antisense Oligonucleotides in Reversing Drug Resistance
The development of new anticancer drugs and the identification of novel targets
2025-01-21 8 -
Ex Vivo Generation of Human Red Blood Cells: A New Advance in Stem Cell Engineering
We describe a technological approach permitting the massive expansion of CD34+ s
2025-01-21 8 -
Characterization of the Effects of RanGTP on the Microtubule Cytoskeleton
Ran is a GTPase of the Ras superfamily. Until recently, its primary role was bel
2025-01-21 14 -
内体(endosome)
内体是膜包裹的囊泡结构,有初级内体(early endosome)和次级内体(late endosome)之分, 初级内体通常位于细胞质的外侧,次级内体常位于细
2025-01-21 21 -
Assessment of Myocardial Angiogenesis and Vascularity in Small Animal Models
Therapies that aim to prevent myocardial tissue from dying or to regenerate new
2025-01-21 14 -
Real-Time PCR Quantification of Gene Expression in Embryonic Mouse Tissue
The Gbx family of transcription factors consists of two closely related proteins
2025-01-21 19 -
Atomic Force Microscopy for the Characterization of Proteoliposomes
Atomic Force Microscopy (AFM) is a useful tool for the visualization of soft bio
2025-01-21 12 -
Nuclear Transplantation and Cloning in Mammals
Nuclear transplantation has been used for many years as an investigative tool wi
2025-01-21 21 -
Alkaline Nuclear Dispersion Assays for the Determination of DNA Damage at the Single Cell Level
Over the past three decades the development of methods for visualizing at the ce
2025-01-21 16 -
A High-Throughput siRNA Screening Platform to Identify MYC-Synthetic Lethal Genes as Candidate Thera
Targeted therapeutics toward specific genes and pathways represent the future of
2025-01-21 9 -
Small-Molecule Collection and High-Throughput Colorimetric Assay to Identify PARP1 Inhibitors
During the last few years, poly(ADP-ribose)polymerase (PARP) proteins became a v
2025-01-21 8 -
组成型分泌途径(constitutive secretory pathway)
在这种分泌途径中, 运输小泡持续不断地从高尔基体运送到细胞质膜,并立即进行膜的融合,将分泌小泡中的蛋白质释放到细胞外, 此过程不需要任何信号的触发, 它存在于所
2025-01-21 9