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  • Detection of Chromosome Abnormalities in Leukemia Using Fluorescence In Situ Hybridization

    Detection of Chromosome Abnormalities in Leukemia Using Fluorescence In Situ Hybridization

    Cytogenetic analysis plays a pivotal role in the diagnosis and management of pat

    2025-03-19 11
  • Choline Metabolic Profiling by Magnetic Resonance Spectroscopy

    Choline Metabolic Profiling by Magnetic Resonance Spectroscopy

    The revised version of cancer hallmarks, depicting the biological properties acq

    2025-03-19 12
  • Comparative Genomic Hybridization for Analysis of Changes in DNA Copy Number in Multiple Myeloma

    Comparative Genomic Hybridization for Analysis of Changes in DNA Copy Number in Multiple Myeloma

    Multiple myeloma (MM) is a clonal neoplasm of terminally differentiated plasma c

    2025-03-19 10
  • Comparative Multiplex PCR and Allele-Specific Expression Analysis in Human Lung Cancer: Tools to Fac

    Comparative Multiplex PCR and Allele-Specific Expression Analysis in Human Lung Cancer: Tools to Fac

    When lung cancer is detected, in the majority of cases it cannot be effectively

    2025-03-19 9
  • Tumor Deprivation of Oxygen and Tumor Suppressor Gene Function

    Tumor Deprivation of Oxygen and Tumor Suppressor Gene Function

    Tumor hypoxia originates from the inability of neovasculature to provide an adeq

    2025-03-19 11
  • Antisense Oligonucleotides Targeting RI Subunit of Protein Kinase A: In Vitro and In Vivo Anti-Tumor

    Antisense Oligonucleotides Targeting RI Subunit of Protein Kinase A: In Vitro and In Vivo Anti-Tumor

    cAMP-dependent protein kinase (PKA) is involved in various cellular functions su

    2025-03-19 13
  • Proteomic Profiling of Ovarian Cancer Models Using TMT-LC-MS/MS

    Proteomic Profiling of Ovarian Cancer Models Using TMT-LC-MS/MS

    Herein, we have utilized two cellular models of epithelial ovarian cancer (EOC),

    2025-03-19 9
  • Immunohistochemical Detection of Ornithine Decarboxylase as a Measure of Chemosensitivity Testing

    Immunohistochemical Detection of Ornithine Decarboxylase as a Measure of Chemosensitivity Testing

    The development of reliable methods for the in vitro testing of sensitivity of c

    2025-03-19 12
  • 9 Intracellular Single-Chain Antibodies for Gene Therapy

    9 Intracellular Single-Chain Antibodies for Gene Therapy

    The delineation of the molecular basis of cancer in general, allows for the poss

    2025-03-19 16
  • Multiple Labeling Techniques for Fluorescence Microscopy

    Multiple Labeling Techniques for Fluorescence Microscopy

    As described in Chapter 2 by Brooks, it has long been possible to localize antig

    2025-03-19 11
  • On-Demand Cleavable Linkers for Radioimmunotherapy

    On-Demand Cleavable Linkers for Radioimmunotherapy

    Radioimmunotherapy (RIT) using radiolabeled antibodies or its fragments holds gr

    2025-03-19 11
  • Intratumoral Gene Transfer of the Cytosine Deaminase Gene for the Treatment of Breast Cancer

    Intratumoral Gene Transfer of the Cytosine Deaminase Gene for the Treatment of Breast Cancer

    One of the major limitations of conventional cancer chemotherapy is its lack of

    2025-03-19 9
  • Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR)

    Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR)

    In this section, we describe the use of Applied Biosystems TaqMan Array microRNA

    2025-03-19 11
  • Genetic Epidemiology Studies in Hereditary Non-Polyposis Colorectal Cancer

    Genetic Epidemiology Studies in Hereditary Non-Polyposis Colorectal Cancer

    Genetic epidemiology studies in hereditary non-polyposis colorectal cancer (HNPC

    2025-03-19 12
  • Detection of Telomerase Enzyme Activity by TRAP Assay

    Detection of Telomerase Enzyme Activity by TRAP Assay

    The telomeric repeat amplification protocol (TRAP) assay, first published by Kim

    2025-03-19 14