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Cytogenetic Studies Using FISH: Background
Prior to the early 1970s, chromosome spreads were block stained with, for exampl
2025-03-18 14 -
Fluorescence In Situ Hybridization: Application in Cancer Research and Clinical Diagnostics
An opportunity to look inside of the individual cell for the direct visualizatio
2025-03-18 15 -
Inflammatory Bowel Disease: A Model of Chronic Inflammation-Induced Cancer
Chronic inflammation is a well-recognized risk factor for the development of hum
2025-03-18 10 -
Detection of Telomerase hTERT Gene Expression and Its Splice Variants by RT-PCR
The finite growth potential of normal cells is termed “cellular senescence” and
2025-03-18 16 -
The Use of Fluorescent Probes in the Study of Reactive Oxygen Species in Pancreatic Cancer Cells
The use of fluorescent probes can be an easy and quick method to analyze whether
2025-03-18 13 -
Mining Expressed Sequence Tag (EST) Libraries for Cancer-Associated Genes
Originally established in the beginning of the 1990s as a direct route to gene f
2025-03-18 10 -
Assays for HSP90 and Inhibitors
The molecular chaperone HSP90 is currently under investigation as a promising ta
2025-03-18 11 -
Regulatory Aspects for Translating Gene Therapy Research into the Clinic
Gene therapy products are highly regulated, therefore moving a promising candida
2025-03-18 11 -
99mTc-Annexin A5 Uptake and Imaging to Monitor Chemosensitivity
Most anticancer agents act by inducing apoptosis in sensitive tumor cells. Hence
2025-03-18 11 -
Microsatellite Analysis of the Insulin-Like Growth Factor II Receptor in Colorectal Carcinomas
The insulin-like growth factor II (IGFII) growth control pathway is comprised of
2025-03-18 10 -
Frozen Biopsy Collection and Storage: Frozen Biopsy Samples
This chapter describes some simple standard operating procedures for the regular
2025-03-18 14 -
Chromosomal Copy Number Analysis in Melanoma Diagnostics
The majority of melanocytic neoplasms can be correctly diagnosed using routine h
2025-03-18 11 -
Rocking Adhesion Assay System to Study Adhesion and Transendothelial Migration of Cancer Cells
Adhesion of metastatic cancer cells to the vascular endothelium of the target or
2025-03-18 12 -
DNA Methylation Changes in Prostate Cancer
Epigenetic alterations contribute significantly to the development and progressi
2025-03-18 10 -
Detection of MicroRNAs in Cultured Cells and Paraffin-Embedded Tissue Specimens by In Situ Hybridiza
Determination of gene expression is essential for understanding the role of a gi
2025-03-18 15
