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2-DE-Based Proteomics for the Analysis of Metastasis-Associated Proteins
Two-dimensional electrophoresis (2-DE) is a high-resolution technique for analys
2025-03-18 10 -
Targeting the Mitochondria to Enhance Tumor Suppression
A continuous supply of biochemical energy is required in order for cells to perf
2025-03-18 11 -
High-Throughput Technology: Green Fluorescent Protein to Monitor Cell Death
Reliable assessment of cell death is now pivotal to many research programs aimin
2025-03-18 11 -
A High-Throughput Methodology for Identifying Molecular Targets Overexpressed in Lung Cancers
As discussed in previous chapters, lung cancer is one of most deadly diseases an
2025-03-18 11 -
Assessment of Insulin-Like Growth Factors and Mutagen Sensitivity as Predictors of Lung Cancer Risk
Insulin-like growth factors (IGFs) are mitogenic peptide hormones involved in th
2025-03-18 10 -
Some Difficult Choices in Cytogenetics
It is rare for a full-fledged malignancy cytogenetics service to be started as a
2025-03-18 11 -
Analysis of the Potential for Pancreatic Cancer Metastasis In Vitro and In Vivo
Pancreatic cancer remains a challenging disease, with an overall 5-year survival
2025-03-18 11 -
Animal Models of Endotoxic Shock
Endotoxin/lipopolysaccharide (LPS) is the major mediator that triggers the cellu
2025-03-18 11 -
Coculture of Prostate Cancer Cells
The progression of prostate cancer is accompanied by the breakdown of normal epi
2025-03-18 15 -
Multiple Myeloma: Challenges and Opportunities
Multiple myeloma (MM) is a B-cell neoplasm in which malignant plasma cells accum
2025-03-18 16 -
Construction and Characterization of RNase-Based Targeted Therapeutics
Cell targeting agents such as antibodies, antibody fragments (sFvs), or growth f
2025-03-18 13 -
The Effects of Butyrate and the Role of c-myc in N.1 Ovarian Carcinoma Cells Determined by Northern
Two hypothetical concepts are discussed as means to cure cancer: 1) extinction o
2025-03-18 11 -
RNase Protection Assay Analysis of mRNA for TGF1-3 in Ovarian Tumors
RNase protection assays provide a level of sensitivity some 20-50-fold greater t
2025-03-18 10 -
Serum and Tissue Biomarkers in the Prognosis and Treatment of Breast Cancer
Several nuclear and membrane proteins are emerging as important markers of breas
2025-03-18 12 -
The rapid progress in understanding the molecular biology of cancer cells has made a large impact on
Phosphorodiamidate morpholino oligomers (PMO), which have a neutral chemistry, a
2025-03-18 10