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Methods to Analyze the Effects of the Urokinase System on Cancer Cell Adhesion, Proliferation, Migra
For cellular-invasive processes during a variety of physio- and pathophysiologic
2025-03-18 13 -
Regulation of Angiostatin Mobilization by Tumor-Derived Matrix Metalloproteinase-2
In recent years, the observation that many endogenous angiogenesis inhibitors ar
2025-03-18 17 -
Intratumoral Gene Transfer of the HLA-B7 Gene Into Colon Carcinoma Metastases
Colorectal adenocarcinoma, with more than 150,000 new cases diagnosed in the Uni
2025-03-18 14 -
Identification of Tumor-Associated Antigens as Diagnostic and Predictive Biomarkers in Cancer
Many studies demonstrated that cancer sera contain antibodies which react with a
2025-03-18 15 -
Detection of Low Levels of DNA Fragmentation in Ovarian Tumor Cell Lines
The techniques presented in this chapter describe the experimental procedure for
2025-03-18 15 -
Polymerase Chain Reaction Based Methods for Assessing Chimerism Following Allogeneic Bone Marrow Tra
It is important to be able to assess the contribution of donor cells to the graf
2025-03-18 16 -
Genetic Modification of Cell Lines to Enhance Their Metastatic Capability
Metastasis is the final step in tumor progression from a benign cell to a fully
2025-03-18 16 -
Tumor Necrosis Factor as a Pharmacological Target
Tumor necrosis factor (TNF) was originally described as a molecule with antitumo
2025-03-18 14 -
Practical Methods for Tissue Microarray Construction
The tissue microarray (TMA) of Kononen et al. is an extension of an idea origina
2025-03-18 16 -
Quantitative, Competitive RT-PCR Analysis of Biomarkers in the Study of Neoplasia
The current status of the evaluation of many neoplasias (e.g., carcinoma of the
2025-03-18 22 -
Detection of Chromosomal Aberrations in Lung Tissue and Peripheral Blood Lymphocytes Using Interphas
Many cancers arise from gene-environment interactions, where susceptible individ
2025-03-18 14 -
Tumor-Targeted Salmonella: Strain Development and Expression of the HSV-tK Effector Gene
Gene therapy approaches to cancer treatment have been limited by the ability of
2025-03-18 18 -
Use of Diphenylamine in the Detection of Apoptosis
The diphenylamine assay is a very useful tool in measuring apoptosis by determin
2025-03-18 19 -
Diagnosis and Monitoring of AML1-MTG8 (ETO)-Positive Acute Myeloid Leukemia by Qualitative and Real-
Assessing the level of residual disease in leukemia is vital for evaluating pati
2025-03-18 12 -
Isolation and Culture of Renal Cancer Cell Lines
Renal cell carcinoma (RCC) represents approximately 2% of all cancers and accoun
2025-03-18 14