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Epidemiology of Brain Tumors
Gliomas account for more than 70% of all brain tumors, and of these, glioblastom
2025-03-17 12 -
TUNEL Assay as a Measure of Chemotherapy-Induced Apoptosis
Chemotherapy induces injury to tumor cells, which subsequently die by a number o
2025-03-17 9 -
Molecular Analysis of Genetic Instability Caused by Chronic Inflammation
Genetic instability is a hallmark of human cancers. It is the driving force for
2025-03-17 14 -
Inhibiting Proinflammatory NF-B Signaling Using Cell-Penetrating NEMO Binding Domain Peptides
Nuclear factor kappa B (NF-κB) is an inducible transcription factor that regulat
2025-03-17 11 -
Assessment of Gelatinases (MMP-2 and MMP-9 by Gelatin Zymography
The invasion and metastasis of tumor cells has been shown to require proteolytic
2025-03-17 11 -
Detection of t(2;5)(p23;q35)Translocation by Long-Range PCR of Genomic DNA
Many types of human leukemias and lymphomas are associated with specific chromos
2025-03-17 17 -
The Use of Matrigel to Facilitate the Establishment of Human Cancer Cell Lines as Xenografts
Matrigel is a solubilized tissue basement membrane matrix rich in extracellular
2025-03-17 30 -
The Contribution of Niche-Derived Factors to the Regulation of Cancer Cells
In normal adult tissues, paracrine signals that derive from the stem cell niche,
2025-03-17 22 -
Extraction of Nucleic Acid Templates
The following series of short technical descriptions covers the extraction of DN
2025-03-17 20 -
Coimmunoprecipitation Assay for the Detection of Kinase-Substrate Interactions
Coimmunoprecipitation is a powerful tool to study protein-protein interactions a
2025-03-17 12 -
Inflammation and Tumor Progression: A Lesson from TNF--Dependent FAK Signaling in Cholangiocarcinoma
Focal Adhesion Kinase (FAK) is implicated in a wide array of cellular processes
2025-03-17 15 -
Economical Protocol for Combined Single-Strand Conformation Polymorphism and Heteroduplex Analysis o
Combined single-strand conformational polymorphism (SSCP) and heteroduplex (HD)
2025-03-17 16 -
Clonality Studies in Cancer Based on X Chromosome Inactivation Phenomenon
The understanding that human neoplasms are clonal cell proliferations ultimately
2025-03-17 15 -
Gene Profiling Uncovers Retinoid Target Genes
Decades of hypothesis-driven research have identified candidate targets for canc
2025-03-17 9 -
Microarray-Based Transcriptome Profiling of Ovarian Cancer Cells
Transcriptome profiling is a powerful method for monitoring genes and their expr
2025-03-17 10