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  • Epidemiology of Brain Tumors

    Epidemiology of Brain Tumors

    Gliomas account for more than 70% of all brain tumors, and of these, glioblastom

    2025-03-17 12
  • TUNEL Assay as a Measure of Chemotherapy-Induced Apoptosis

    TUNEL Assay as a Measure of Chemotherapy-Induced Apoptosis

    Chemotherapy induces injury to tumor cells, which subsequently die by a number o

    2025-03-17 9
  • Molecular Analysis of Genetic Instability Caused by Chronic Inflammation

    Molecular Analysis of Genetic Instability Caused by Chronic Inflammation

    Genetic instability is a hallmark of human cancers. It is the driving force for

    2025-03-17 14
  • Inhibiting Proinflammatory NF-B Signaling Using Cell-Penetrating NEMO Binding Domain Peptides

    Inhibiting Proinflammatory NF-B Signaling Using Cell-Penetrating NEMO Binding Domain Peptides

    Nuclear factor kappa B (NF-κB) is an inducible transcription factor that regulat

    2025-03-17 11
  • Assessment of Gelatinases (MMP-2 and MMP-9 by Gelatin Zymography

    Assessment of Gelatinases (MMP-2 and MMP-9 by Gelatin Zymography

    The invasion and metastasis of tumor cells has been shown to require proteolytic

    2025-03-17 11
  • Detection of t(2;5)(p23;q35)Translocation by Long-Range PCR of Genomic DNA

    Detection of t(2;5)(p23;q35)Translocation by Long-Range PCR of Genomic DNA

    Many types of human leukemias and lymphomas are associated with specific chromos

    2025-03-17 17
  • The Use of Matrigel to Facilitate the Establishment of Human Cancer Cell Lines as Xenografts

    The Use of Matrigel to Facilitate the Establishment of Human Cancer Cell Lines as Xenografts

    Matrigel is a solubilized tissue basement membrane matrix rich in extracellular

    2025-03-17 30
  • The Contribution of Niche-Derived Factors to the Regulation of Cancer Cells

    The Contribution of Niche-Derived Factors to the Regulation of Cancer Cells

    In normal adult tissues, paracrine signals that derive from the stem cell niche,

    2025-03-17 22
  • Extraction of Nucleic Acid Templates

    Extraction of Nucleic Acid Templates

    The following series of short technical descriptions covers the extraction of DN

    2025-03-17 20
  • Coimmunoprecipitation Assay for the Detection of Kinase-Substrate Interactions

    Coimmunoprecipitation Assay for the Detection of Kinase-Substrate Interactions

    Coimmunoprecipitation is a powerful tool to study protein-protein interactions a

    2025-03-17 12
  • Inflammation and Tumor Progression: A Lesson from TNF--Dependent FAK Signaling in Cholangiocarcinoma

    Inflammation and Tumor Progression: A Lesson from TNF--Dependent FAK Signaling in Cholangiocarcinoma

    Focal Adhesion Kinase (FAK) is implicated in a wide array of cellular processes

    2025-03-17 15
  • Economical Protocol for Combined Single-Strand Conformation Polymorphism and Heteroduplex Analysis o

    Economical Protocol for Combined Single-Strand Conformation Polymorphism and Heteroduplex Analysis o

    Combined single-strand conformational polymorphism (SSCP) and heteroduplex (HD)

    2025-03-17 16
  • Clonality Studies in Cancer Based on X Chromosome Inactivation Phenomenon

    Clonality Studies in Cancer Based on X Chromosome Inactivation Phenomenon

    The understanding that human neoplasms are clonal cell proliferations ultimately

    2025-03-17 15
  • Gene Profiling Uncovers Retinoid Target Genes

    Gene Profiling Uncovers Retinoid Target Genes

    Decades of hypothesis-driven research have identified candidate targets for canc

    2025-03-17 9
  • Microarray-Based Transcriptome Profiling of Ovarian Cancer Cells

    Microarray-Based Transcriptome Profiling of Ovarian Cancer Cells

    Transcriptome profiling is a powerful method for monitoring genes and their expr

    2025-03-17 10