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Quantitative Determination of p16 Gene Expression by RT-PCR
In recent years, gene expression quantitation of tumor cells has become of princ
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Direct Sequencing for Juvenile Polyposis Gene SMAD4/DPC4 Mutations
Juvenile polyposis (JP) is a rare dominantly inherited tumor predisposition synd
2025-03-15 22 -
Tumor Suppressor Genes in Lung Cancer
Lung cancer is the number-one cancer killer of both men and women in the United
2025-03-15 19 -
Cell Separations by Flow Cytometry
Flow cytometry has become a standard method for separating individual subsets of
2025-03-15 15 -
Transforming Growth Factor Beta: A Plasma Tumor Marker
Malignant tumors have been known for many years to release proteins or polypepti
2025-03-15 14 -
Strategies for the Use of Site-Specific Recombinases in Genome Engineering
Conventional gene targeting has been very useful in the study of gene function a
2025-03-15 15 -
Molecular Mechanisms of Drug Resistance in Single-Step and Multi-Step Drug-Selected Cancer Cells
Multidrug resistance (MDR) remains one of the key determinants in chemotherapeut
2025-03-15 13 -
In Vitro Model of Spontaneous Mouse OSE Transformation
An in vitro syngeneic model of neoplastic progression of murine ovarian surface
2025-03-15 11 -
Quantitative and Spatial Image Analysis of Tumor and Draining Lymph Nodes Using Immunohistochemistry
Immunohistochemistry is an essential tool for clinical and translational researc
2025-03-15 16 -
Engineering Hot Spots for Affinity Enhancement of Antibodies
The potential of antibodies as magic bullets for targeting therapeutic drugs or
2025-03-15 16 -
Gene Expression Profile Analysis of Tumors
Gene expression profiling is a powerful tool to analyze the complexity of cancer
2025-03-15 9 -
Use of the Polymerase Chain Reaction Technique to Detect the t(14;18) Translocation in Lymphoid Tiss
The t(14;18) (q32;21) chromosomal translocation is characteristic of follicle ce
2025-03-15 12 -
Nanoparticle Characterization for Cancer Nanotechnology and Other Biological Applications
Nanotechnology is actively being used to develop promising diagnostics and thera
2025-03-15 14 -
Direct Kinase Assay Screening for Inhibitors of MAP Kinase
An important convergence point involved in the signal transduction pathways of m
2025-03-15 10 -
Using In Vivo Biopanning for the Development of Radiation-Guided Drug Delivery Systems
This chapter illustrates our protocol for in vivo biopanning using T7 bacterioph
2025-03-15 11
