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Genetic Polymorphisms in the Transforming Growth Factor-β Signaling Pathways and Breast Cancer Risk
The transforming growth factor (TGF)-β signaling pathway plays a critical role i
2025-03-15 10 -
Quantitative Immunohistochemistry of Estrogen and Progesterone Receptor Positivity in Ovarian Tumors
Several assays exist to determine receptor status in ovarian cancers, like radio
2025-03-15 10 -
Detection of Circulating Tumor Cells by Photoacoustic Flowmetry
Detection of circulating tumor cells (CTCs) in human blood and lymph systems has
2025-03-15 12 -
Development of Bacterial Vectors for Tumor-Targeted Gene Therapy
Gene therapy holds great promise for the treatment of cancer. The success of the
2025-03-15 15 -
Analysis of EMT by Flow Cytometry and Immunohistochemistry
Ovarian cancer stem cells (OCSCs) are in a transitional phase between epithelial
2025-03-15 14 -
Prediction of the Biological Effect of Polymorphisms Within MicroRNA Binding Sites
MicroRNAs (miRNAs) are negative gene regulators acting at the 3′UTR level, modul
2025-03-15 13 -
Comparative Genomic Hybridization
Comparative genomic hybridization (CGH ) allows a genome-wide survey of the rela
2025-03-15 10 -
Breast Cancer Proteomics Using Two-Dimensional Electrophoresis: Studying the Breast Cancer Proteome
Proteomics has emerged as a powerful approach for studying disease-associated ch
2025-03-15 21 -
PCR Microsatellite Analysis of LOH in Ovarian Tumors
The “two-hit” theory of tumor suppressor gene (TSG) inactivation predicts that l
2025-03-15 18 -
The EGFR Pathway as an Example for Genotype: Phenotype Correlation in Tumor Genes
Tumor-specific and germ-line variations of DNA significantly contribute to tumor
2025-03-15 10 -
Transfection Assays for Transformation of Model Colonic Cell Lines
The recognition of cancer as a genetic disease has changed the approach investig
2025-03-15 7 -
Solving Problems in Multiplex FISH
Over the last 15 yr, advances in molecular biology have allowed improvements in
2025-03-15 16 -
Marker Utility for Combination Therapy
Melanoma is a heterogeneous disease for which monotherapies are likely to fail i
2025-03-15 20 -
Compartmentalized Protein Kinase C Activation in Ovarian Carcinoma Cells
Protein kinase C (PKC), a family of phospholipid-dependent serine/threonine kina
2025-03-15 11 -
Overexpression of PRV-1 Gene in Polycythemia Rubra Vera and Essential Thrombocythemia
The polycythemia rubra vera 1 gene (PRV-1 ), a member of the urokinase-type plas
2025-03-15 11
