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Methods for Chemoprotection and Chemosensitization: MDR-1 For Chemoprotection Using Retroviruses to
Surgery, radiation therapy, and chemotherapy have been applied to the curative t
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Fluorescence In Situ Hybridization and Comparative Genomic Hybridization
This chapter discusses the complementary methodologies of fluorescence in situ h
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Ethics of Cancer Gene Transfer Clinical Research
Cancer gene transfer is a relatively novel intervention strategy. In part becaus
2025-03-15 13 -
Lung-Specific Expression of Mutant p53 as Mouse Model for Lung Cancer
The p53 tumor suppressor gene is the most commonly mutated gene in cancer (1 ,2)
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Metabolomics of Cancer
Metabolomics, one of the “omic” sciences in systems biology, is the global asses
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Classification of AML by DNA-Oligonucleotide Microarrays
Accurate diagnosis and classification of leukemias are the bases for the appropr
2025-03-15 9 -
Determining Mutational Status of Immunoglobulin V Genes in Chronic Lymphocytic Leukemia: A Useful Pr
Determining the clonal origins of malignant B-cells will have an impact on disea
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Positional Approaches to Cancer Genetics
Loss of genetic material accumulates during tumor development as cancer cells se
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Use of the Differential Staining Cytotoxicity Assay to Predict Chemosensitivity
The differential staining cytotoxicity (DiSC) assay is one of the total cell-kil
2025-03-15 10 -
Tissue Resources for Clinical Use and Marker Studies in Melanoma
The adequate procurement and preservation of high-quality tissue specimens from
2025-03-15 10 -
Analysis of Cancer Stem Cell Metastasis in Xenograft Animal Models
Metastatic spread of cancer cells from the primary tumors to distant vital organ
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Clinical Implications of Epigenetic Alterations in Human Thoracic Malignancies: Epigenetic Alteratio
Besides known genetic aberrations, epigenetic alterations have emerged as common
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Generation of Genetically Modified Embryonic Stem Cells for the Development of Knockout Mouse Animal
The aim of our lab is to understand the contributions made by cell adhesion mole
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Genome-Wide Methylation Analysis
The disruption and alteration of genomic methylation patterns is a hallmark of c
2025-03-15 9 -
High-Throughput Mutation Screening Using a Single Amplification Condition
Numerous innovative and high-throughput techniques have been established to iden
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