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Assaying the Spindle Checkpoint in the Budding Yeast Saccharomyces cerevisiae
The spindle checkpoint is assayed in Saccharomyces cerevisiae using several crit
2025-03-15 13 -
Detection of Rearrangements in the bcl-2 Gene Using the Polymerase Chain Reaction
Described here is a simple polymerase chain reaction (PCR) method for detecting
2025-03-15 11 -
Meta-analysis of Cancer Gene-Profiling Data
DNA microarray profiles are plagued by the issue of large number of variables bu
2025-03-15 11 -
Demonstration of a Germinal Center Immunophenotype in Lymphomas by Immunocytochemistry and Flow Cyto
The germinal center plays an important role in the pathogenesis of B-cell lympho
2025-03-15 12 -
Humanization of Monoclonal Antibodies by CDR Grafting
The discovery of the process for making rodent monoclonal antibodies (MAbs) 26 y
2025-03-15 9 -
Detection of Aberrant Glycosylation in Breast Cancer Using Lectin Histochemistry
Lectins are naturally occurring, carbohydrate-binding molecules that can be isol
2025-03-15 11 -
Detection of Telomerase Activity by PCR-Based Assay
Telomeres are distal ends of human chromosomes composed of tandem repeats of the
2025-03-15 10 -
Epigenetics in Ovarian Cancer
Ovarian cancer is the most lethal gynecological cancer. Due to few early symptom
2025-03-15 16 -
Use of DNA Fingerprinting to Detect Genetic Rearrangements in Human Cancer
The polymerase chain reaction (PCR) has revolutionized the isolation and analysi
2025-03-15 10 -
Analyzing the Function of Tumor Suppressor Genes Using a Drosophila Model
With 1600 eyes, a pair of antennae, 6 legs, and an open circulatory system, the
2025-03-15 11 -
Clinical Implications of p53 Mutations in Lung Cancer
The p53 tumor-suppressor gene plays a crucial role in the cellular response to s
2025-03-15 14 -
Detection of Apoptosis in Ovarian Cells In Vitro and In Vivo Using the Annexin V-Affinity Assay
The ability of a cell to undergo apoptosis is crucial during development, tissue
2025-03-15 9 -
Drug Delivery Approaches for Ovarian Cancer Therapy
Tumor-specific drug delivery represents a challenging issue that restricts the c
2025-03-15 9 -
Current Applications of Nanotechnology for Magnetic Resonance Imaging of Apoptosis
Apoptosis, or programmed cell death, is a morphologically and biochemically dist
2025-03-15 9 -
Genetic Manipulation of Yeast to Identify Genes Involved in Regulation of Chemosensitivity
Fission and budding yeast have been regarded as valuable tools for studying seve
2025-03-15 11
