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An Overview: From Discovery of Candidate Mutations to Disease Modeling and Transformation Mechanisms
Acute leukemia is an aggressive form of hematological malignancy, which is chara
2025-03-15 16 -
Surgical Treatment of Lung Cancer: Past And Present
From the fortuitous beginning of surgery of the chest in the 15th century to the
2025-03-14 10 -
A Method for Conducting Highly Sensitive MicroRNA In Situ Hybridization and Immunohistochemical Anal
Profiling experiments in whole tissue biopsies have linked altered expression of
2025-03-14 10 -
Cloning of Immunoglobulin Chromosomal Translocations by Long-Distance Inverse Polymerase Chain React
Many subtypes of B-cell malignancy are characterized by chromosomal translocatio
2025-03-14 10 -
Clinical Application of Tissue and Serum Markers in Breast Cancer
How different the practice of oncology would become if physicians could predict
2025-03-14 9 -
Novel Approaches to Screen for Anticancer Drugs Using Saccharomyces cerevisiae
The development of anticancer drugs has relied primarily on two traditional appr
2025-03-14 12 -
Prioritizing Candidate Genetic Modifiers of BRCA1 and BRCA2 Using a Combinatorial Analysis of Global
Epidemiological evidence from different studies has shown that genes harboring s
2025-03-14 10 -
Abrogation of the RB-p16Tumor Suppressor Pathway in Human Lung Cancer
There is compelling evidence that human lung cancers are characterized by disrup
2025-03-14 9 -
Challenges in Experimental Modeling of Ovarian Cancerogenesis
Ovarian cancer is a complex disease, with unclear origins, complicated, multiste
2025-03-14 13 -
Optimal Molecular Profiling of Tissue and Tissue Components: Defining the Best Processing and Microd
Isolation of well-preserved pure cell populations is a prerequisite for sound st
2025-03-14 13 -
Co-immunoprecipitation of Tumor Suppressor Protein-Interacting Proteins
Tumor suppressor proteins, like most proteins, require interacting with other pr
2025-03-14 10 -
Detection of Chromosomal Deletions by Microsatellite Analysis
Microsatellites are tandem repeats of simple sequence, 2–6 bp, that occur abunda
2025-03-14 12 -
Immunocytochemical Detection and Characterization of Individual Micrometastatic Tumor Cells
Early hematogenous spread of cancer cells must be regarded as major cause for th
2025-03-14 11 -
Microsatellite Instability Testing
Microsatellites are tandem repeats of simple sequences that occur abundantly and
2025-03-14 11 -
Ultrasound Techniques for the Detection of Tumors and Metastases in Small Animals
Small animals are widely used for the identification of new therapeutic targets
2025-03-14 12