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Virus Production for Clinical Gene Therapy
Gene therapy is becoming increasingly relevant for the treatment of prominent hu
2025-03-14 16 -
Cell Cycle Checkpoint Control Mechanisms That Can Be Disrupted in Cancer
Maintenance of genomic integrity is essential to avoid cellular transformation,
2025-03-14 21 -
Expression Analysis of Homeobox Genes in Leukemia/Lymphoma Cell Lines
Homeobox genes code for transcription factors which have a strong impact on cell
2025-03-14 16 -
Antisense Oligonucleotide Inhibitors of MDM2 Oncogene Expression
Antisense therapy represents a novel genetic-based therapeutic approach, initiat
2025-03-14 21 -
Use of Nanoparticles for Targeted, Noninvasive Thermal Destruction of Malignant Cells
Shortwave (MHz range) radiofrequency (RF) energy is nonionizing, penetrates deep
2025-03-14 17 -
Digital Single-Nucleotide Polymorphism Analysis for Allelic Imbalance
Digital single-nucleotide polymorphism (SNP) analysis is developed to amplify a
2025-03-14 15 -
Single-Chain Fv-Based Affinity Purification of the Cellular Stress Protein gp96 for Vaccine Developm
Cellular stress proteins like the classical heat-shock proteins (HSPs) hsp70 (1
2025-03-14 19 -
Isolation of Circulating MicroRNAs from Microvesicles Found in Human Plasma
Intact miRNAs can be isolated from the circulation in significant quantities des
2025-03-14 15 -
Epigenetics of Solid Cancer Stem Cells
Epigenetics is an emerging science that can help to explain carcinogenesis. The
2025-03-14 17 -
Enhanced Mismatch Mutation Analysis: Simultaneous Detection of Point Mutations and Large Scale Rearr
We present the routine diagnostic application of EMMA (Enhanced Mismatch Mutatio
2025-03-14 13 -
Rapid Identification of Chromosomes Using Primed In Situ Labeling (PRINS)
Primed in situ labeling (PRINS) was introduced by Koch and colleagues (1 ) for t
2025-03-14 12 -
Generating Inhibitors of P-Glycoprotein: Where to, Now
The prominent role for the drug efflux pump ABCB1 (P-glycoprotein) in mediating
2025-03-14 14 -
Generation, Expression, and Monitoring of Recombinant Immune Receptors for Use in Cellular Immunothe
Cellular immunotherapy has attracted increasing interest in genetic modification
2025-03-14 13 -
Immunological and Gene Therapy for Ovarian Cancer A Technical Overview
Conventional medical approaches are limited in part on the prognosis of ovarian
2025-03-14 11 -
Identification of Murine and Human Acute Myeloid Leukemia Stem Cells
There is now compelling evidence to show that tumors, once believed to be a homo
2025-03-14 10