-
Multiplex PCR (MPCR) Screening Can Detect Small Intragenic p53 Deletion and Insertion Mutations
Mutations of the p53 tumor suppressor gene are the most common alterations assoc
2025-03-13 18 -
Statistical Considerations in the Analysis of Tumor Markers
In this chapter, we will lay out the basics of experimental design: how to organ
2025-03-13 10 -
Relationship of EGFR Signal-Transduction Modulation by Tyrosine Kinase Inhibitors to Chemosensitivit
Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein of 170 k
2025-03-13 10 -
Dissection of Tumor and Host Cells from Metastasized Organs for Testing Gene Expression Directly Ex
The interaction between tumor and host cells determines to a large extent the ou
2025-03-13 13 -
Imaging Specific Cell Surface Protease Activity in Living Cells Using Reengineered Bacterial Cytotox
The scarcity of methods to visualize the activity of individual cell surface pro
2025-03-13 10 -
Molecular Epidemiology of Human Cancer Risk: Gene-Environment Interactions and p53 Mutation Spectrum
Epidemiology has identified several etiological factors in lung cancer, of which
2025-03-13 18 -
Purification and Analysis of Checkpoint Protein Complexes From Saccharomyces cerevisiae
The DNA damage-dependent checkpoint of Saccharomyces cerevisiae is a paradigm fo
2025-03-13 14 -
Magnetic Resonance Imaging of Metastases in Xenograft Mouse Models of Cancer
Magnetic resonance imaging (MRI) of small animals has emerged as a valuable tool
2025-03-13 14 -
Targeting of Nanoparticles: Folate Receptor
Nanoparticulate medicines offer the advantage of allowing delivery of large quan
2025-03-13 11 -
Laser-Assisted Microdissection and Isolation of DNA and RNA
One of the major challenges in molecular analysis of breast cancer specimens is
2025-03-13 13 -
Induced Nitric Oxide Synthase as a Major Player in the Oncogenic Transformation of Inflamed Tissue
Nitric oxide (NO) is a free radical that is involved in the inflammatory process
2025-03-13 13 -
Caspase-3 Activation is a Critical Determinant of Genotoxic Stress-Induced Apoptosis
A number of methods have been developed to identify the cells that undergo apopt
2025-03-13 12 -
Flow Cytometric MRD Detection in Selected Mature B-Cell Malignancies
The quantification of submicroscopic minimal residual disease (MRD) after therap
2025-03-13 11 -
Immunomagnetic Cell Separation
In metastasis research, it may sometimes be necessary to separate populations of
2025-03-13 13 -
Molecular Analysis of Cancer: An Overview
Cancer is a complex disease occurring as a result of a progressive accumulation
2025-03-13 14
