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Detecting Mismatch Repair Defects in Myeloma
Defects in the mismatch repair system are associated with a microsatellite unsta
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Gene Expression Profiling to Characterize Anticancer Drug Sensitivity
This chapter presents a protocol for using cDNA microarrays to acquire gene expr
2025-03-13 9 -
Immunohistochemistry of p53, Bcl-2, and Ki-67 as Predictors of Chemosensitivity
Chemosensitivity is affected by molecular biological factors, including factors
2025-03-13 10 -
DNA-Dependent Protein Kinase in Apoptosis
Programmed cell death or apoptosis can be induced by a variety of mechanisms inc
2025-03-13 11 -
PARP Cleavage as a Means of Assessing Apoptosis
Although cell death is often seen as a pathological process, there are classical
2025-03-13 12 -
Dietary and Lifestyle Factors of DNA Methylation
Lifestyle factors, such as diet, smoking, physical activity, and body weight man
2025-03-13 10 -
Biomarkers of Cell Proliferation in Carcinomas: Detection of Angiogenesis and Infiltrated Leukocytes
Angiogenesis is an important marker for tumor growth, development, and metastasi
2025-03-13 10 -
Traditional and Established Indicators of Prognosis and Treatment Success
The outcome of breast cancer in an individual patient can be predicted by assess
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Calibration of Microarray Gene-Expression Data
Calibration of microarray measurements aims at removing systematic biases from t
2025-03-13 10 -
Gene Targeting to Hepatomas (AFP)
Hepatocellular carcinoma (HCC) is one of the most common malignancies with poor
2025-03-13 12 -
Measurement of Protein Expression of p53, p21WAF1, and Rb in Patients with Surgically Treated Hepato
Hepatocellular carcinoma (HCC) is one of the most common human malignancies in t
2025-03-13 14 -
Assays for Proteasome Inhibition
The ubiquitin-proteasome pathway has an essential role in the regulation of nume
2025-03-13 9 -
Direct Analysis for Familial Adenomatous Polyposis Mutations
Over the past decade, the genes that underlie the development of many human dise
2025-03-13 9 -
Gene Therapy of Glioblastoma Multiforme with a Bicistronic Retroviral Vector Expressing Human IL-2 a
Gene therapy of cancer includes strategies for augmentation of immunotherapeutic
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Rescue and Isolation of Rb-deficient Prostate Epithelium by Tissue Recombination
The ability to rescue viable prostate precursor tissue from Rb−/− fetal mice has
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