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20Telomere Length Changes in Human Cancer
Telomere length is now known to be directly responsible for limiting the capacit
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Microarrays for Protease Detection in Tissues and Cells
Expression of a given protease and of the endogenous inhibitors that regulate pr
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Identifying the Origin and Phenotype of Cells in Tumor Xenografts
The growth of human tumor cells transplanted into immunodeficient mice is freque
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Application of Proteomics in Cancer Gene Profiling: Two-Dimensional Difference in Gel Electrophoresi
In the post-genomic era, proteomic strategies are at the forefront of cancer res
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High-Throughput RNA Sequencing in B-Cell Lymphomas
High-throughput mRNA sequencing (RNA-seq) uses massively parallel sequencing to
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Serial Biopsies/Fine-Needle Aspirates and Their Assessment
Taking a series of repeat biopsies or fine needle aspirates of a tumor during th
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Histoculture Drug Response Assay to Monitor Chemoresponse
We provide a detailed explanation of the procedure of the histoculture drug resp
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HSV-1 Vectors for Gene Therapy of Experimental CNS Tumors
Gliomas account for about 60% of all primary CNS tumors; two-thirds of all gliom
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Growth of Prostatic Epithelial and Stromal Cells In Vitro
Well-established techniques are now in place to culture several of the major typ
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Determination of Cancer Allelotype
The term “allelotype” was first used by Vogelstein and colleagues (1 ), in analo
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Mutation Analysis of Large Genomic Regions in Tumor DNA Using Single-Strand Conformation Polymorphis
In recent years, we have seen a dramatic improvement in our ability to detect nu
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Induction of Programmed Cell Death with an Antisense Bcl-2 Oligonucleotide
Limited advances have occurred in lung cancer prevention and treatment (1 ), whi
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Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma
The cancer stem cell hypothesis states that within a tumor only a subset of cell
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Quantitative Real-Time PCR Expression Analysis of Peripheral Blood Mononuclear Cells in Pancreatic C
The ability of peripheral blood mononuclear cells (PBMCs) to act as a surrogate
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High-Sensitivity Cytotoxicity Assays for Nonadherent Cells
High-sensitivity cytotoxicity assays refer to assays that can detect high levels
