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Clinical Development of Antisense Oligonucleotides as Anti-Cancer Therapeutics
Antisense oligonucleotides (AONs) are one of the several types of “antisense the
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Molecular Characterization of Melanoma-Derived Antigens
In the last decade, many antigens expressed by tumors and recognized by the immu
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Chemosensitization of Tumor Cells: Inactivation of Nuclear Factor-Kappa B Associated with Chemosensi
Combination chemotherapy has been shown to be more effective than single-agent t
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Elucidation of Signal Transduction Pathways by Transfection of Cells with Modified Oncogenes
This chapter will focus on introduction of various wild type (WT) and mutant gen
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Risk Factors and Gene Expression in Esophageal Cancer
Esophageal cancer is a significant worldwide health problem because of its poor
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Discovery of Antibody Biomarkers Using Protein Microarrays of Tumor Antigens Cloned in High Throughp
Development of humoral and cellular immunity against self-cellular proteins in c
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Phosphatidylinositol 4-Kinase Assay in Ovarian Carcinoma Cells
Membrane-constituting phospholipids include glycerol phospholipids such as phos-
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Clinically Accurate Orthotopic Mouse Models of Cancer
In the past 10 years, we have developed a new approach to the development of a c
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Cancer Cohort Consortium Approach: Cancer Epidemiology in Immunosuppressed Groups
Nearly 40 years have passed since the publication of the first report showing hi
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Epidemiology of Stomach Cancer
Despite a major decline in incidence and mortality over several decades, stomach
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In Vivo Footprinting and DNA Affinity Chromatography for Analysis of p53 DNA Binding Ability
p53 is a sequence-specific DNA binding protein. The p53 consensus is two copies
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Cytogenetic Studies Using FISH: Background
Prior to the early 1970s, chromosome spreads were block stained with, for exampl
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Fluorescence In Situ Hybridization: Application in Cancer Research and Clinical Diagnostics
An opportunity to look inside of the individual cell for the direct visualizatio
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Inflammatory Bowel Disease: A Model of Chronic Inflammation-Induced Cancer
Chronic inflammation is a well-recognized risk factor for the development of hum
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Detection of Telomerase hTERT Gene Expression and Its Splice Variants by RT-PCR
The finite growth potential of normal cells is termed “cellular senescence” and
