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A High-Throughput siRNA Screening Platform to Identify MYC-Synthetic Lethal Genes as Candidate Thera
Targeted therapeutics toward specific genes and pathways represent the future of
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Small-Molecule Collection and High-Throughput Colorimetric Assay to Identify PARP1 Inhibitors
During the last few years, poly(ADP-ribose)polymerase (PARP) proteins became a v
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组成型分泌途径(constitutive secretory pathway)
在这种分泌途径中, 运输小泡持续不断地从高尔基体运送到细胞质膜,并立即进行膜的融合,将分泌小泡中的蛋白质释放到细胞外, 此过程不需要任何信号的触发, 它存在于所
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Detection of NF-B Activity in Skeletal Muscle Cells by Electrophoretic Mobility Shift Analysis
An electrophoretic mobility shift assay (EMSA) is a common and invaluable techni
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Methods for Iodination of Active TGF, TGF Receptor Crosslinking and Immunoprecipitation of TGF-Recep
Radioiodinated transforming growth factors ( TGF-βs) are critical reagents for f
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Analysis of Neuromuscular Junctions: Histology and In Vivo Imaging
The formation of new synapses within neuronal circuits is considered a primary m
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Feeder-Independent Maintenance of Human Embryonic Stem Cells and Directed Differentiation into Endot
Human embryonic stem cells (hESCs) represent a promising source of cells for mod
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Covisualization of Methylcytosine, Global DNA, and Protein Biomarkers for In Situ 3D DNA Methylation
DNA methylation and histone modifications are key regulatory mechanisms in cellu
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Methods for Analysis of Ligand-Induced RNA Conformational Changes
Encoded within many RNA sequences is the requisite information for folding of in
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Sources and Derivation of Human Embryonic Stem Cells
Human embryonic stem cells (hESCs) are pluripotent cells derived from the inner
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Master Cell Bank
Master Cell BankAuthor: Nanci DonackiSource: Contributed by Nanci DonackiAbstrac
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PNA-In Situ Hybridization Method for Detection of HIV-1 DNA in Virus-Infected Cells and Subsequent D
We describe in situ hybridization protocols using peptide nucleic acid (PNA) as
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Recording Ion Channels in Isolated, Split-Opened Tubules
Ion channels play key roles in physiology. They function as protein transducers
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Raman Micro-Spectroscopy as a Non-invasive Cell Viability Test
The number of techniques to identify, quantify and characterise cell death is ra
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Tiny Molecular Beacons for in vivo mRNA Detection
The molecular beacon technology is an established approach for visualizing nativ