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Optimal Molecular Profiling of Tissue and Tissue Components: Defining the Best Processing and Microd
Isolation of well-preserved pure cell populations is a prerequisite for sound st
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Co-immunoprecipitation of Tumor Suppressor Protein-Interacting Proteins
Tumor suppressor proteins, like most proteins, require interacting with other pr
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Detection of Chromosomal Deletions by Microsatellite Analysis
Microsatellites are tandem repeats of simple sequence, 2–6 bp, that occur abunda
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Immunocytochemical Detection and Characterization of Individual Micrometastatic Tumor Cells
Early hematogenous spread of cancer cells must be regarded as major cause for th
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Microsatellite Instability Testing
Microsatellites are tandem repeats of simple sequences that occur abundantly and
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Ultrasound Techniques for the Detection of Tumors and Metastases in Small Animals
Small animals are widely used for the identification of new therapeutic targets
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Reconstruction of Geno-Phenotypic Evolutionary Sequences from Intracellular Patterns of Molecular Ab
In this chapter we describe an approach to the analysis of human tumors that emp
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Cytogenetics of Solid Tumours
The study of chromosome abnormalities in solid tumours provides valuable informa
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Experimental Models and Methods in Antibody Targeting of Renal Cell Carcinoma
Metastatic renal cell carcinoma (RCC) is incurable and there are few treatment o
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Cancer Biology
The process of carcinogenesis involves a number of changes in cellular phenotype
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Identification of Clonotypic IgH VDJ Sequences in Multiple Myeloma
In multiple myeloma (MM) the rearranged immunoglobulin heavy chain (IgH) variabl
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Methods for the Study of Protein-Protein Interactions in Cancer Cell Biology
Development of sensitive methods to monitor and quantitatively assess the expres
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Serial Analysis of Gene Expression (SAGE)
In 1995, serial analysis of gene expression (SAGE) was developed as a versatile
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Immunophenotyping of Plasma Cells in Multiple Myeloma
Multiparametric immunophenotyping of multiple myeloma (MM) and other plasma cell
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Cytogenetic Methods in Chronic Lymphocytic Leukemia
In chronic lymphocytic leukemia of the B-lineage (B-CLL), cytogenetic alteration