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Xenopus Cell-Free Extracts to Study the DNA Damage Response
Cell-free systems derived from Xenopus eggs represent a powerful tool, intermedi
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Anchorage-Independent Growth of Prostate Cancer Stem Cells
Prostate cancer is a major health concern in the Western world. Prostate cancer
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Mutation Detection in Colorectal Cancers: Direct Sequencing of DNA Mismatch Repair Genes
The detection of unknown mutations has proved complex and time consuming, and th
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Gene Expression Microarrays
New methods have been developed for determining and monitoring gene expression l
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Detection of Apoptosis in Renal Cell Carcinoma
Apoptosis is a selective process of programmed cell death that plays an importan
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I1307K Mutation Detection by Allele-Specific PCR in Familial Colorectal Cancer
Familial colorectal cancer (FCC) is a hereditary form of colorectal cancer that
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Reciprocal Subtraction Differential RNA Display (RSDD): An Efficient Technology for Cloning Differen
Identification of differentially expressed genes is an essential step in compreh
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Invasion and Motility Assays
A key feature of malignant cells is their capacity to invade surrounding tissue
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Pathological Evaluation of Axillary Sentinel Lymph Nodes in Breast Cancer
Nodal staging is the most important prognostic factor in the management of patie
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Intratumoral Injection of Naked DNA
Direct injection of naked DNA into tissues as a gene-delivery method has been ex
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Measurement of IGF-1 Receptor Content in Tissues and Cell Lines by Radioimmunoassay (RIA) and ELISA
The IGF-1 receptor (IGF-1-R) belongs to the tyrosine kinase growth factor recept
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VHL and Kidney Cancer
Kidney cancer affects approximately 30,000 individuals in the United States and
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Measurement of DNA Damage in Individual Cells Using the Single Cell Gel Electrophoresis (Comet) Assa
The Single Cell Gel Electrophoresis (Comet) assay is a simple, versatile and sen
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Integrating Multiple Types of Data to Identify MicroRNAGene Co-modules
MicroRNAs (miRNAs) and genes work cooperatively to form the kernel part of gene
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Generation of Antibody Molecules Through Antibody Engineering
Twenty-five years ago, Georges K�hler and C�sar Milstein invented a means of clo
