The ISCOM Technology
Classical adjuvant formulations, such as Freund’s adjuvants and aluminium salts,
Classical adjuvant formulations, such as Freund’s adjuvants and aluminium salts, are blended with antigens to formulate an emulsion, or the antigens are adsorbed onto a three-dimensional gel containing adjuvant (1 ). The ISCOM™ (immunostimulating complex, Iscotec AB, Uppsala, Sweden) is a complex consisting of lipids, saponins, and antigens, which form spontaneously when the right constituents are allowed to interact at correct stoichiometry.
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