CD50分子

CD50 分子   CD50 常用单克隆抗体或代号： 101- 1D2,140- 11;(ICAM- 3) 主要表达细胞： Leu [AS] 分子质量(kDa)和结构： gp120(IgSF) 功    能： 粘附,CD11a- CD11b/CD18配基,信号转导和共刺激   CD50 Aka ICAM-3; ligand for LFA-1 (CD54) Provides adhesion signals important in B-T cell interactions Important in MHC restricted interaction between T cells and target cells Regulates leukocyte morphology Positive staining (normal): leukocytes, epidermal Langerhans cells, endothelial cells Negative staining: non-hemaoietic cells