CD41分子

CD41 分子   CD41 常用单克隆抗体或代号： PBM6.4,PL273(integrin a Ⅱb) 主要表达细胞： Pt,Meg [Pt] 分子质量(kDa)和结构： gp120/23 功    能： 血小板凝集和活化Fb,结合ECM(FB,vWF)的受体,与CD61组成二聚体   CD41 Aka platelet GPIIb Receptor for fibrinogenin, von Willebrand factor and fibronectin Mutations cause thrombasthenia Positive staining (normal): platelets, megakaryocytes Positive staining (disease): AML M7, blasts in transient myeloproliferative disorder