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Engineering Hot Spots for Affinity Enhancement of Antibodies
The potential of antibodies as magic bullets for targeting therapeutic drugs or
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Gene Expression Profile Analysis of Tumors
Gene expression profiling is a powerful tool to analyze the complexity of cancer
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Use of the Polymerase Chain Reaction Technique to Detect the t(14;18) Translocation in Lymphoid Tiss
The t(14;18) (q32;21) chromosomal translocation is characteristic of follicle ce
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Nanoparticle Characterization for Cancer Nanotechnology and Other Biological Applications
Nanotechnology is actively being used to develop promising diagnostics and thera
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Direct Kinase Assay Screening for Inhibitors of MAP Kinase
An important convergence point involved in the signal transduction pathways of m
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Using In Vivo Biopanning for the Development of Radiation-Guided Drug Delivery Systems
This chapter illustrates our protocol for in vivo biopanning using T7 bacterioph
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Analysis of Growth Properties and Cell Cycle Regulation Using Mouse Embryonic Fibroblast Cells
A balance between proliferation and apoptosis is crucial for cellular homeostasi
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In Situ Hybridization in Cancer and Normal Tissue
With recent advances in the Human Genome Project and progress in microarray and
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DNA Immunization as a Means to Generate Antibodies to Proteins
For over a century now, antibodies have proven to be extremely useful reagents i
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Measurement of Estrogen Receptor Status by Immunocytochemistry in Paraffin Wax Sections
The estrogen receptor (ER) status and, to a lesser extent, progesterone receptor
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Quantitative PCR Detection of c-erbB-2 Gene Amplification
The association of c-erbB-2 oncogene amplification and prognostic factors was in
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Identification and Analysis of Precursors to Invasive Pancreatic Cancer
Histologically distinct noninvasive precursor lesions have been recognized in th
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RNA Purification and Quantification Methods
Analysis of gene expression within tumors is frequently performed on the messeng
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Use of siRNA to Study the Function of MDC1 in DNA Damage Responses
Small interfering RNA (siRNA) technology has emerged as a powerful genetic tool
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Complete Array of HOX Gene Expression by RQ-PCR
In mammals the HOX network consists of 39 genes which encode master regulators o
