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Production of Plasmid DNA as a Pharmaceutical
Developments in gene therapy, cell therapy, and DNA vaccination require a pharma
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Functional Analysis of Tumor Suppressor Genes in Mice
The utilization of mice as a model for human cancer goes back to the generation
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Microarray-Based Comparative Genomic Hybridization (Array-CGH) as a Useful Tool for Identifying Gene
Alterations in the genome that lead to changes in DNA sequence copy number are a
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Immunoscope Analysis of T-Lymphocytes Infiltrating Melanocytic Tumors
Melanomas are most frequently infiltrated by actively proliferating T-lymphocyte
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The Chick Embryo Metastasis Model
The growth and dissemination of malignant tumors continues to have a devastating
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The Regulation of Tumor Suppressor Genes by Oncogenes
Tumor suppressor genes (TSGs) and oncogenes represent the ying and the yang of c
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Cancer Gene Profiling in Prostate Cancer
Gene profiling and expression analysis using microarrays have made a significant
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Detection and Analysis of DNA Methylation by Pyrosequencing
Pyrosequencing is a “sequencing by synthesis” technique which can be used to qua
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Non-RI Protocols for L-myc Allelotyping and Deletion Mapping of Chromosome 1p in Primary Lung Cancer
Deletion at a specific locus in a chromosome in cancer cells is assumed to imply
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Cyclooxygenase Inhibitors Induce Colon Cancer Cell Apoptosis Via PPAR 14-3-3 Pathway
Non-steroidal anti-inflammatory drugs (NSAIDs) and selective cyclooxygenase-2 (C
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Apoptosis Assessment by the DNA Diffusion Assay
A simple, sensitive, and reliable DNA diffusion assay for quantification of apop
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Epigenetic Targets in Cancer Epidemiology
Recently, it has been shown that epigenetic changes are involved in early stages
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Molecular and Genetic Aspects of Lung Cancer
Lung cancer is the leading cause of cancer death among men and women in the Unit
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Genetic Analysis of Drug Resistance by Fluorescence In Situ Hybridization
Tumor progression is driven by the accumulation of genetic changes, which, in ag
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Detection of Apoptosis by the TUNEL Assay
Apoptosis is the name given to a normal cell process—that of programmed cell dea
